Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
Shop by
-
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Optimal Electrolyte Sticks
4.8Rated 4.8 out of 5 stars5 ReviewsFrom $40Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full details -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Optimal Focus
4.6Rated 4.6 out of 5 stars108 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
View full details -
Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Optimal Magnesium
4.9Rated 4.9 out of 5 stars617 ReviewsFrom$20$17Key Benefits and Actions† Lysinate, glycinate, and malate forms of magnesium for optimal bioavailability Supports GI comfort, relaxation, and na...
View full details -
Get the high-strength, methyl-free prenatal you need to protect you and your baby’s health with Optimal Prenatal MF!†
Optimal Prenatal MF—The first non-methylated prenatal vitamin of its kind that includes bioavailable and well-tolerated sources of B12 and folate that are absolutely critical for prenatal health.†
Optimal Prenatal MF
4.9Rated 4.9 out of 5 stars67 ReviewsFrom $65Key Benefits and Actions† Formulated with 32 researched ingredients in the right amounts. Supports healthy immune, spine, and brain development...
View full details -
Get the upper hand on stress by supporting feelings of calm and mood balance with Phosphatidyl Serine!†
Phosphatidyl Serine—A phospholipid that supports a healthy stress response with 150 mg of non-GMO sunflower-sourced phosphatidylserine per capsule.†
Phosphatidyl Serine
4.8Rated 4.8 out of 5 stars43 ReviewsFrom $45Key Benefits and Actions† Supports healthy concentration and cognition Supports feelings of calm and healthy mood Helps to support a healthy str...
View full details -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Prenatal Essentials MF
5.0Rated 5.0 out of 5 stars91 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full details -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota HistaminX!†
ProBiota HistaminX—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
ProBiota HistaminX
4.8Rated 4.8 out of 5 stars1,245 ReviewsFrom$40$34Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
View full details -
Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
Riboflavin
4.9Rated 4.9 out of 5 stars99 ReviewsFrom $24Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...
View full details -
Get reliable, scientifically-backed information at your fingertips anytime by signing up for the Seeking Health Educational Institute's Yearly Membership!
Seeking Health Educational Institute Yearly Membership—Includes unlimited access to 100+ hours of education, monthly live videos and Q&A’s with Dr. Ben Lynch, and a free copy of Dr. Lynch’s best-selling book, “Dirty Genes.”
Seeking Health Educational Institute Yearly Membership
5.0Rated 5.0 out of 5 stars6 ReviewsFrom $95 -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars111 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details