Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars139 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
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Foster healthy energy production and mood with methyl-free B Complex MF.†
B Complex MF—A potent B vitamin complex containing the 8 essential B vitamins, featuring non-methylated B12 and folate in the forms of Hydroxo B12 and folinic acid.†
B Complex MF
4.6Rated 4.6 out of 5 stars100 ReviewsFrom $30Key Benefits and Actions† Methyl-free vitamin B complex Supports healthy energy production Supports a healthy mood Who Needs B Complex MF Have...
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Promote healthy energy production and mood without additional B12 and folate with B Minus.†
B Minus—A potent formula containing 6 essential B vitamins that’s free from B12 and folate to allow for customization of these two essential nutrients.†
B Minus
4.8Rated 4.8 out of 5 stars243 ReviewsFrom $30Key Benefits and Actions† Vitamin B complex free of B12 and folate Supports healthy energy production Supports healthy mood Who Needs B Minus ...
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Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™️ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™️.†
Brain Nutrients
4.6Rated 4.6 out of 5 stars56 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
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Support normal liver and gut detoxification and healthy cholesterol and estrogen levels with Calcium D-Glucarate.†
Calcium D-Glucarate—Contains 250 mg of calcium D-glucarate, a form of glucaric acid that is stabilized with calcium to support your body’s healthy natural detoxification function.†
Calcium D-Glucarate
4.9Rated 4.9 out of 5 stars120 ReviewsFrom $32Key Benefits and Actions† Supports liver & gut detoxification Supports normal estrogen metabolism Supports normal cholesterol levels Who Ne...
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Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars143 ReviewsFrom $43Key Benefits and Actions† Supports healthy liver metabolism of estrogens Supports detoxification and elimination Supports healthy inflammatory r...
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Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
Dopamine Nutrients
4.7Rated 4.7 out of 5 stars27 ReviewsFrom $46Supports healthy mood and motivation Supports healthy energy levels in the brain Antioxidants support brain health Who Needs Dopamine Nutrients ...
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Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid
4.8Rated 4.8 out of 5 stars168 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
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Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars179 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
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Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Hydroxo B12 with Folinic Acid
4.8Rated 4.8 out of 5 stars188 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
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Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
4.6Rated 4.6 out of 5 stars22 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
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Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
Lithium Orotate—Provides a low serving of lithium (5 mg per capsule) as lithium orotate attached to the natural compound orotic acid for optimal bioavailability and efficient absorption.†
Lithium Orotate
4.8Rated 4.8 out of 5 stars92 ReviewsFrom $22Key Benefits and Actions† Supports feelings of calm and well-being Natural mood support Supports memory, brain, and neurological health Who Nee...
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Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Liver Nutrients
4.9Rated 4.9 out of 5 stars326 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
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Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
4.8Rated 4.8 out of 5 stars110 ReviewsFrom $22Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
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Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
4.7Rated 4.7 out of 5 stars170 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
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Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
4.9Rated 4.9 out of 5 stars181 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
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Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars262 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
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Customize your vitamin intake to support your specific health needs—especially if you have sensitivities—with Multivitamin Sensitive!†
Multivitamin Sensitive—A customizable multivitamin and mineral supplement. It is strategically formulated without certain nutrients to allow for individual serving size customization.†
Multivitamin Sensitive
4.5Rated 4.5 out of 5 stars51 ReviewsFrom$45$38.25Key Benefits and Actions† Customizable multivitamin Free from folate, B12, copper, iron, iodine, vitamins D and K, and calcium Stress regulation...
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Optimal Electrolyte
4.6Rated 4.6 out of 5 stars1,426 ReviewsFrom$38$32.30Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, Hi...
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A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Optimal Electrolyte Sticks
4.8Rated 4.8 out of 5 stars5 ReviewsFrom $40Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
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Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Optimal Focus
4.6Rated 4.6 out of 5 stars108 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
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Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Optimal Magnesium
4.9Rated 4.9 out of 5 stars619 ReviewsFrom$20$17Key Benefits and Actions† Lysinate, glycinate, and malate forms of magnesium for optimal bioavailability Supports GI comfort, relaxation, and na...
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Get the high-strength, methyl-free prenatal you need to protect you and your baby’s health with Optimal Prenatal MF!†
Optimal Prenatal MF—The first non-methylated prenatal vitamin of its kind that includes bioavailable and well-tolerated sources of B12 and folate that are absolutely critical for prenatal health.†
Optimal Prenatal MF
4.9Rated 4.9 out of 5 stars67 ReviewsFrom $65Key Benefits and Actions† Formulated with 32 researched ingredients in the right amounts. Supports healthy immune, spine, and brain development...
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Get the upper hand on stress by supporting feelings of calm and mood balance with Phosphatidyl Serine!†
Phosphatidyl Serine—A phospholipid that supports a healthy stress response with 150 mg of non-GMO sunflower-sourced phosphatidylserine per capsule.†
Phosphatidyl Serine
4.8Rated 4.8 out of 5 stars43 ReviewsFrom $45Key Benefits and Actions† Supports healthy concentration and cognition Supports feelings of calm and healthy mood Helps to support a healthy str...
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