Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Prenatal Essentials MF
5.0Rated 5.0 out of 5 stars91 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
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Be kind to your gut while supporting its health with the low-histamine formula of ProBiota HistaminX!†
ProBiota HistaminX—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
ProBiota HistaminX
4.8Rated 4.8 out of 5 stars1,246 ReviewsFrom$40$34Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
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Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
Riboflavin
4.9Rated 4.9 out of 5 stars99 ReviewsFrom $24Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...
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Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars111 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
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